Matrix Advanced Solutions
Peptide Dosing Guide
Stack Protocol

Sermorelin + GHK-Cu

Growth + Collagen Support Stack

What It Is

A synergistic stack pairing Sermorelin — a GHRH analog that stimulates natural growth hormone release — with GHK-Cu, a copper-binding tripeptide that drives collagen remodeling and tissue repair. Together they support GH-mediated recovery while enhancing skin, connective tissue, and overall regeneration.

Stack Rationale

Sermorelin pulses natural GH release, improving sleep, recovery, and body composition. GHK-Cu activates collagen synthesis, anti-inflammatory gene expression, and copper-dependent repair enzymes. The combination produces GH-driven systemic recovery alongside targeted collagen remodeling — ideal for anti-aging, recovery, and connective tissue support.

Critical Administration Note

Separate Syringe and Injection Time Required

GHK-Cu must ALWAYS be administered in a separate syringe and at a separate injection time from Sermorelin. Do not mix in the same syringe.

Benefits

Natural GH release
Collagen remodeling
Improved sleep quality
Skin rejuvenation
Connective tissue repair
Anti-aging gene expression

Dosing Protocol — Sermorelin

Parameter Details
Dose 250 mcg nightly
Route Subcutaneous injection
Timing Before bed, fasted
Schedule 5 days on / 2 days off
Ceiling Do not exceed 250–300 mcg without medical guidance

Dosing Protocol — GHK-Cu

Parameter Details
Dose 2 mg per injection
Timing Morning or post-workout
Frequency 2–3x per week
Route Subcutaneous injection — separate syringe and time from Sermorelin
Cycle 30 days on / 14 days off

Dosing Ratio

Recommended Ratio

1:8 GHK-Cu to Sermorelin (mg:mg). Example: GHK-Cu 2 mg + Sermorelin 250 mcg (0.25 mg) yields approximately a 1:8 ratio.

Protocol Options

Option A — Separate Dosing (Recommended)

Option B — Combined Micro-Dose

Cycling Schedule

Peptide Cycle Pattern
Sermorelin 5 days on / 2 days off
GHK-Cu 30 days on / 14 days off

How To Know It's Working

Safety & Side Effects

This guide is for educational and clinical-support purposes only. All dosing must be supervised by a licensed prescriber. Matrix Advanced Solutions does not provide medical advice. Always consult your healthcare provider before starting any peptide protocol.