Matrix Advanced Solutions
Peptide Dosing Guide
Stack Protocol

MOTS-c + Semax

Energy + Mental Clarity Stack

What It Is

A performance stack pairing mitochondrial-derived MOTS-c with the nootropic peptide Semax. MOTS-c optimizes cellular energy production and metabolic efficiency. Semax enhances BDNF, sharpens focus, and improves cognitive performance under stress. Together they deliver steady physical energy and mental clarity without stimulant crashes.

Stack Rationale

MOTS-c works at the mitochondrial level to improve energy metabolism, AMPK activation, and glucose regulation. Semax works at the neurological level to boost BDNF, enhance attention, and reduce brain fog. The combination targets both physical and cognitive energy — body and brain operating at peak output.

Important Distinction

This is NOT a fat loss stack. It is designed for steady energy output and cognitive performance under stress.

Benefits

Sustained physical energy
Enhanced focus & mental clarity
Improved metabolic efficiency
BDNF upregulation
Stress resilience
Cognitive performance under load

Dosing Protocol — MOTS-c

Parameter Details
Dose Range 5–15 mg per injection
Frequency 2–3x per week
Route Subcutaneous injection
Initial Effects 1–2 weeks
Full Effects 4–6 weeks

Dosing Protocol — Semax

Parameter Details
Dose Range 200–600 mcg daily
Administration Split AM/PM
Route Intranasal
Onset of Effects 3–5 days

Stack Timing & Cycle

Parameter Details
MOTS-c Cycle 4–6 weeks for full metabolic adaptation
Semax Cycle Can be run continuously or cycled 4 weeks on / 1 week off
Semax Onset Cognitive effects noticeable within 3–5 days
MOTS-c Onset Energy improvements within 1–2 weeks, full effects 4–6 weeks

Supportive Supplements

How To Know It's Working

Safety & Side Effects

This guide is for educational and clinical-support purposes only. All dosing must be supervised by a licensed prescriber. Matrix Advanced Solutions does not provide medical advice. Always consult your healthcare provider before starting any peptide protocol.