Matrix Advanced Solutions
Peptide Dosing Guide
Disputed / Gray

5-Amino-1-MQ

NNMT Inhibitor — Marketed for Fat Loss & Longevity (Not Recommended)

Matrix Advisory

Source evidence does not support this compound. Zero convincing human data. Not recommended for Matrix protocols. Do not buy — this is snake oil.

What It Is

5-Amino-1-MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy metabolism. It has been marketed aggressively in the peptide space as a fat-loss and longevity compound. Source assessment: there is no convincing human evidence that it works for either purpose.

Mechanism of Action

Inhibits NNMT, which theoretically increases NAD+ availability and shifts energy metabolism toward fat oxidation. In cell cultures and some rodent models, NNMT inhibition has shown metabolic effects. However, these results have not translated to meaningful outcomes in humans.

Dosing Protocol (Reference Only)

For Reference Only

These doses are provided for informational purposes. Matrix does not recommend this compound. Most users report feeling nothing.

Parameter Details
Starting Dose 25 mg daily
Moderate Dose 50 mg daily
High Dose 100 mg daily
Route Oral
Cycle Length 4–8 weeks
Typical User Experience Most users feel nothing

Recommended Alternatives

Instead of 5-Amino-1-MQ, Matrix recommends compounds with actual evidence:

This guide is for educational and clinical-support purposes only. All dosing must be supervised by a licensed prescriber. Matrix Advanced Solutions does not provide medical advice. Always consult your healthcare provider before starting any protocol.