Melanotan II — Alpha-MSH Analog for Melanin Production & Libido Enhancement
Melanotan II (MT-2) is a synthetic analog of alpha-melanocyte-stimulating hormone (alpha-MSH). It stimulates melanin production in the skin, producing a tan without UV exposure, and has well-documented effects on libido and sexual function in both men and women.
Binds melanocortin receptors (MC1R–MC5R), activating melanogenesis in skin cells. Cross-reactivity with MC3R and MC4R accounts for appetite suppression and sexual arousal effects.
| Parameter | Details |
|---|---|
| Tolerance Test | 50 mcg (first injection) |
| Ramp-Up | Increase by 50 mcg daily for 5–7 days |
| Moderate / Loading | 500–750 mcg daily until base tan achieved |
| High / Loading | 1,500 mcg daily (loading only — not long-term) |
| Maintenance | 1–2 doses per week |
| Route | Subcutaneous injection |
| Initial Results | 1–2 weeks |
| Full Tan | 4–6 weeks |
Gradual Loading Required
Start with a 50 mcg tolerance test and ramp up slowly. Jumping to full dose causes significant nausea and flushing in most users.
Skin Monitoring Required
Regular skin checks are strongly recommended. Monitor all moles and freckles for changes in size, shape, border, or color. Report any changes to your prescriber immediately.
This guide is for educational and clinical-support purposes only. All dosing must be supervised by a licensed prescriber. Matrix Advanced Solutions does not provide medical advice. Always consult your healthcare provider before starting any peptide protocol.