Mitochondrial-Derived Peptide — Energy Metabolism & Insulin Sensitivity
MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome. It acts as a cellular energy regulator, improving glucose uptake and insulin sensitivity while supporting metabolic resilience at the mitochondrial level.
Activates AMPK signaling pathways, enhancing cellular energy metabolism and glucose homeostasis. Supports mitochondrial function, fatty acid oxidation, and insulin sensitivity across metabolically active tissues.
| Parameter | Details |
|---|---|
| Starting Dose | 5 mg 2–3x/week |
| Moderate Dose | 10 mg 2–3x/week |
| High Dose | 15 mg 2–3x/week |
| Route | Subcutaneous injection |
| Initial Effects | 1–2 weeks |
| Full Effects | 4–6 weeks |
Limited Human Data
While preclinical results are promising, human research on MOTS-c remains limited. Prescriber oversight is essential.
This guide is for educational and clinical-support purposes only. All dosing must be supervised by a licensed prescriber. Matrix Advanced Solutions does not provide medical advice. Always consult your healthcare provider before starting any peptide protocol.